Bourne is brought out of hiding once again by reporter Simon Ross who is trying to unveil Operation Blackbriar, an upgrade to Project Treadstone, in a series of newspaper columns. Information from the reporter stirs a new set of memories, and Bourne must finally uncover his dark past while dodging The Company's best efforts to eradicate him.

Posting up at a local watering hole in Roswell, New Mexico, a town infamous for its UFO past, Horowitz and Newton meet with individuals who have experienced strange and unexplainable encounters.