A group of self-absorbed actors set out to make the most expensive war film ever. After ballooning costs force the studio to cancel the movie, the frustrated director refuses to stop shooting, leading his cast into the jungles of Southeast Asia, where they encounter real bad guys.

With the UniSol program budget cut by the government, a gang of mercenaries takes control of the new line of Universal Soldiers for their own nefarious ends. In doing so, they clash with Luc Deveraux, survivor of the first incident with the UniSols, alongside his long-lost and newly-resurrected brother Eric and reporter Veronica Roberts.

A pragmatic U.S. Marine observes the dehumanizing effects the U.S.-Vietnam War has on his fellow recruits from their brutal boot camp training to the bloody street fighting in Hue.

An American soldier who had been killed during the Vietnam War is revived 25 years later by the military as a semi-android, UniSols, a high-tech soldier of the future. After the failure of the initiative to erase all the soldier's memories, he begins to experience flashbacks that are forcing him to recall his past.