The series focuses on an eccentric motley crew that is the Smith family and their three housemates: Father, husband, and breadwinner Stan Smith; his better half housewife, Francine Smith; their college-aged daughter, Hayley Smith; and their high-school-aged son, Steve Smith. Outside of the Smith family, there are three additional main characters, including Hayley's boyfriend turned husband, Jeff Fischer; the family's man-in-a-goldfish-body pet, Klaus; and most notably the family's zany alien, Roger, who is "full of masquerades, brazenness, and shocking antics."

After escaping a calamitous train crash, Ethan realizes The Entity is stashed aboard an old Russian submarine, but a foe from his past named Gabriel is also on the trail.

Robin, Starfire, Raven, Beast Boy and Cyborg return in all-new, comedic adventures. They may be super heroes who save the world every day ... but somebody still has to do the laundry!