A lonely Frankenstein travels to 1930s Chicago to ask groundbreaking scientist Dr. Euphronious to create a companion for him. The two revive a murdered young woman and The Bride is born. But what ensues is beyond what either of them imagined.

Soulmates Eric and Shelly are brutally murdered when the demons of her dark past catch up with them. Given the chance to save his true love by sacrificing himself, Eric sets out to seek merciless revenge on their killers, traversing the worlds of the living and the dead to put the wrong things right.