A man who loves when a plan comes together, Col. Hannibal Smith leads a close-knit team of elite operatives and Iraq War veterans. Framed for a crime they didn't commit, Smith and his men, Capt. H.M. ‘Howling Mad’ Murdock , Sgt. Bosco ‘B.A.’ Baracus, and Lt. Templeton ‘Faceman’ Peck, break out and go rogue, using their special talents to clear their names and find the perpetrator. Hot on their trail is Capt. Charissa Sosa, who was once involved with a member of Smith's team and has sworn to capture them, no matter what it takes.

When an IMF mission ends badly, the world is faced with dire consequences. As Ethan Hunt takes it upon himself to fulfill his original briefing, the CIA begin to question his loyalty and his motives. The IMF team find themselves in a race against time, hunted by assassins while trying to prevent a global catastrophe.