Follow five work-obsessed twenty-somethings striving for professional success and, if they have time, personal happiness in Manhattan's most glamorous neighborhood, Murray Hill.

Fighting crime full-time as Spider-Man in a world that doesn't remember him—and the pressure of seeing his old friends move on without him—sparks a change in Peter Parker he may not have the power to control. But that transformation might also be the only thing that can stop a shocking new threat to the city and those he loves - a powerful villain no one can even see.

Two love-starved strangers crash into each other on the one night of the year when single people are allowed to have sex.

Ben Reilly, an aging and down on his luck private investigator in 1930s New York, is forced to grapple with his past life as the city's one and only superhero.

Andy Sachs returns to Runway as Miranda Priestly navigates a new media landscape and Runway's position within. The duo reconnect with former assistant Emily Charlton, now the head of a luxury brand that possesses funding which could ensure Runway's survival.

A woman answers a help wanted ad to be a housekeeper in a mysterious New York City high-rise, unaware that she is entering a community that has seen a number of disappearances over the years and may be under the grip of a Satanic cult.

Following the latest Ghostface killings, the four survivors leave Woodsboro behind and start a fresh chapter.

Eight years after the original website went dark, a new generation of New York private school teens are introduced to the social surveillance of Gossip Girl.

Mark and his 12-year-old daughter’s lives were changed forever 10 years earlier when she was turned into a vampire. Locked in at age 12, perhaps forever, Eleanor lives a closed-in life, able to go out only at night, while her father does his best to provide her with the minimal amount of human blood she needs to stay alive.

It’s 1882 and the Gilded Age is in full swing when Marian Brook, a young orphaned daughter of a Southern general, moves in with her rigidly conventional aunts in New York City. With the help of Peggy Scott, an African-American woman masquerading as her maid, Marian gets caught up in the dazzling lives of her rich neighbors as she struggles to decide between adhering to the rules or forging her own path.

The first live-action TV series based on the popular comic book.

When by-the-book FBI Special Agent Bill Goodman is loaned out to a clandestine CIA/FBI task force, he finds himself teamed up with secretive and roguish CIA case officer Colin Glass. Together they work covert operations in New York, uncovering international plots, terrorist cells, and geopolitical secrets.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

In this musical comedy, optimistic high school teacher Will Schuester tries to refuel his own passion while reinventing the high school's glee club and challenging a group of outcasts to realize their star potential as they strive to outshine their singing competition while navigating the cruel halls of McKinley High.

An exclusive group of privileged teens from a posh prep school on Manhattan's Upper East Side whose lives revolve around the blog of the all-knowing albeit ultra-secretive Gossip Girl.