Doctor Strange, with the help of mystical allies both old and new, traverses the mind-bending and dangerous alternate realities of the Multiverse to confront a mysterious new adversary.

After his career is destroyed, a brilliant but arrogant surgeon gets a new lease on life when a sorcerer takes him under her wing and trains him to defend the world against evil.

Queen Ramonda, Shuri, M’Baku, Okoye and the Dora Milaje fight to protect their nation from intervening world powers in the wake of King T’Challa’s death. As the Wakandans strive to embrace their next chapter, the heroes must band together with the help of War Dog Nakia and Everett Ross and forge a new path for the kingdom of Wakanda.

King T'Challa returns home to the reclusive, technologically advanced African nation of Wakanda to serve as his country's new leader. However, T'Challa soon finds that he is challenged for the throne by factions within his own country as well as without. Using powers reserved to Wakandan kings, T'Challa assumes the Black Panther mantle to join with ex-girlfriend Nakia, the queen-mother, his princess-kid sister, members of the Dora Milaje (the Wakandan 'special forces') and an American secret agent, to prevent Wakanda from being dragged into a world war.

Super-Hero partners Scott Lang and Hope van Dyne, along with with Hope's parents Janet van Dyne and Hank Pym, and Scott's daughter Cassie Lang, find themselves exploring the Quantum Realm, interacting with strange new creatures and embarking on an adventure that will push them beyond the limits of what they thought possible.

Just when his time under house arrest is about to end, Scott Lang once again puts his freedom at risk to help Hope van Dyne and Dr. Hank Pym dive into the quantum realm and try to accomplish, against time and any chance of success, a very dangerous rescue mission.